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Biopharmaceutical
Technology
Unit
2017
Tyrosine-Triazolinedione Bioconjugation as Site-Selective Protein Modification starting from RAFT-derived Polymers. Vandewalle S, De Coen R, De Geest, BG; Du Prez FE. ACS Macro Letters in press
Acrylamides with hydrolytically labile carbonate ester side chains as versatile building blocks for well-defined block copolymer micelles via RAFT polymerization. Kasmi S, Louage B, Nuhn L, Verstraete G, Van Herck S,, van Steenbergen MJ, Hennink WE, Vervaet C, De Geest BG. Polymer Chemistry in press
Cancer cell lysate entrapment in CaCO3 engineered with polymeric TLR-agonists: immune-modulating microparticles in view of personalised antitumor vaccination. Lybaert L, Ryu KA, De Rycke R, De Wever O, Chon AC, Esser-Kahn AP, De Geest BG. Chemistry of Materials 2017, 29, 4209
Polyelectrolyte-enrobed cancer cells in view of personalized immunotherapy
Lybaert L, De Rycke R, De Wever O, Vermaelen K, Esser-Kahn A, De Geest BG. Advanced Science 2017, 1700050
Developments and future clinical outlook of taxane nanomedicines. Louage B, Hennink WE, De Wever O, De Geest BG. Journal of Controlled Release 2017, 253, 137
Micellar paclitaxel-initiated RAFT polymer conjugates with acid-sensitive behavior. Louage B, Van Steenbergen MJ, Nuhn L, Risseeuw MDP, Karalic I, Winne J, Van Calenbergh S, Hennink WE, De Geest BG. ACS Macro Letters 2017, 6, 272.
Poly(glycerol sebacate) nanoparticles for facile loading of hydrophobic anti-cancer drugs. Louage B, Tack L, Wang Y, De Geest BG. Polymer Chemistry in press
Transiently thermoresponsive polymers and their applications in biomedicine. Vanparijs N, Nuhn L, De Geest BG. Chemical Society Reviews 2017, 46, 1193
Amphiphillic ferrocene-containing PEG-block copolymers micellar nano carriers and smart surfactants. Alkan A, Wald S, Louage B, De Geest BG, Landfester K, Wurm FR. Langmuir 2017, 33, 272.
Immobilization of 2-deoxy-D-ribose-5-phosphate aldolase in polymeric thin films via the Langmuir-Schaefer technique. Reinicke S, Rees HR, Espeel P, Vanparijs N, Bitterfeld C, Dick M, Rosenkranz RR, Brezesinski, De geest BG, Du Prez FE, Pietruszka J, Böker A. ACS Applied Materials and Interfaces 2017, 9, 8317
Arginine-rich peptide-based mRNA nanocomplexes efficiently instigate cytotoxic T cell immunity dependent on the amphiphatic organisation of the peptide. Udhayakumar VK, De Beuckelaer A, McCaffrey J, McRudden, Kirschman JL, Vanover D, Van Hoecke L, Roose K, Deswarte K, De Geest BG, Lienenklaus S, Santangelo PJ, Grooten J, McCarthy HO, De Koker S. Advanced Healthcare Materials, in press
Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12. De Koker S, Van Hoecke L, De Beuckelaer A, Roose K, Deswarte K, Willart MA, Bogaert P, Naessens T, De Geest BG, Saelens X, Lambrecht BN, Grooten J. Scientific Reports, in press
Preparation and Characterization of Alginate Microparticles Containing a Model Protein for Oral Administration in Gnotobiotic European Sea Bass (Dicentrarchus labrax) Larvae. Yaacob EN, Goethals J, Bajek A, Dierckens K, Peter Bossier, De Geest BG, Vanrompay D. Marine Biotechnology, in press
Thermoplastic Polyurethane-Based Intravaginal Rings For Prophylaxis and Treatment of (Recurrent) Bacterial Vaginosis. Verstraete G, Vandenbussche L, Kasmi S, Nuhn L, Brouckaert D, Van Renterghem J, Grymonpré W, T. Coenye T, De Geest BG, De Beer T, Remon J, Vervaet C. International Journal of Pharmaceutics, in press
Coumarin-containing thermoresponsive hyaluronic acid-based nanogels as delivery systems for anticancer chemotherapy. Stefanello TF, Couturaud B, Szarpak-Jankowska A, Fournier D, Louage B, Garcia FP, Nakamura CV, De Geest BG, Woisel P, van der Sanden B, Auzély-Velty R. Nanoscale, in press
Uptake of long protein-polyelectrolyte nanotubes by dendritic cells. Ramirez-Wong D, Saghazadeh S, Van Herck S, De Geest B, Jonas A, Demoustier-Champagne S. Biomacromolecules, in press
2016
Well-defined polymeric pactlitaxel prodrugs via a grafting-from-drug approach
Louage B, Nuhn L, Risseeuw MPD, Vanparijs N, De Coen R, Karalic I, Van Calenbergh S, De Geest BG
Angewandte Chemie International Edition 2016, 55, 11791.
Core/shell protein-reactive nanogels via a combination of RAFT polymerization and vinyl sulfone post-modification
Vanparijs N, Nuhn L, Paluck AJ, Kokkinopoulou M, Lieberwirth I, Maynard HD, De Geest BG
Nanomedicine 2016, 20, 2631.
pH-degradable mannosylated nanogels for dendritic cell targeting
De Coen R, Vanparijs N, Risseeuw M, Lybaert L, Louage B, De Koker S, Kumar V, Grooten J, Taylor L, Ayres N, Van Calenberghh S, Nuhn L, De Geest BG
Biomacromolecules 2016, 17, 2479.
pH-degradable imidazoquinoline-ligated nanogels for lymph node focused immune activation
Nuhn L, Vanparijs N, De Beuckelaer A, Lybaert L, Verstraete G, Deswarte K, Lienenklaus S, Shukla NM, Salyer ACD, Lambrecht NB, Grooten J, David SA, De Koker S, De Geest BG
Proceedings of the National Academy of Sciences 2016, 113, 8098.
Salt-driven deposition of of thermo-responsive polymer-coated metal nanoparticles on solid substrates
Zhang Z, Samarendra M, Antunes A, De Rycke R, Hoogenboom R, De Geest BG
Angewandte Chemie International Edition 2016, 55, 7086.
Thermally induced charge reversal of layer-by-layer assembled singla-component films
Richardson, J.J.; Tardy, B.L.; Ejima, H.; Guo, J.; Cui, J.; Liang, K.; Choi, G.H.; Yoo, P.J.; De Geest, B.G.; Caruso, F.
ACS Applied Materials & Interfaces 2016, 8, 7449.
Super resolution imaging of nanoparticles cellular uptake and trafficking
van der Zwaag, D.; Vanparijs, N.; Wijnands, S.; De Rycke, R.; De Geest, B.G.; Albertazzi, L.
ACS Applied Materials & Interfaces 2016, 8, 6391.
A generic polymer-protein ligation strategy for vaccine delivery
Lybaert, L.; Vanparijs, N.; Fierens, K.; Schuijs, M.; Nuhn, L.; Lambrecht, B.N.; De Geest, B.G.
Biomacromolecules 2016, 17, 874.
Influenza-binding sialylated polymer coated gold nanoparticles prepared via RAFT polymerization and reductive amination
Zhang, Z.; Schepens, B.; Nuhn, L.; Saelens, X.; Schotsaert, M.; Callewaert, N.; De Rycke, R.; Zhang, Q.; Moins, S.; Benali, S.; Mespouille, L.; Hoogenboom, R.; De Geest, B.G.
Chemical Communications 2016, 52, 3352.
pH-independent immediate release polymethacrylate formulations - an observational study
Claeys, B.; Vandeputte, R.; De Geest, B.G.; Remon, J.P.; Vervaet, C.
Drug Development and Industrial Pharmacy 2016, 42, 578.
Spontaneous protein adsorption on graphene oxide nanosheets allows efficient intracellular vaccine protein delivery
Li, H.; Fierens, K.; Zhang, Z.; Vanparijs, N.; Schuijs, M.; Van Steendam, K.; Deiner Garcia, N.; De Rycke, R.; De Beer, T.; De Beuckelaer, A.; De Koker, S.; Deforce, D.; Albertazzi, L;. Grooten, J.; Lambrecht, B.N.; De Geest, B.G.;
ACS Applied Materials & Interfaces 2016, 8, 1147.
Transiently responsive block copolymer micelles based on HPMA engineered with hydrolysable ethylcarbonate side chains.
Kasmi, S.; Louage, B.; Nuhn, L.; Van Driessche, A.; Van Deun, J.; Karalic, I.; Risseeuw, M.; Can Calenbergh, S.; Hoogenboom, R.; De Rycke, R.; De Wever, O.; Hennink, W.E.; De Geest, B.G.
Biomacromolecules 2016, 17, 119.
Engineering polymer hydrogel nanoparticles for lymph node targeted delivery
De Koker, S.; Cui, J.; Vanparijs, N.; Albertazzi, L.; Grooten, J.; Caruso, F.; De Geest, B.G.
Angewandte Chemie International Edition 2016, 55, 1334.
Poly(N-isopropylacrylamide) coated gold nanoparticles as colourimetric temperature and salt sensors
Maji, S.; Cesur, B.; Zhang, Z.; De Geest, B.G.; Hoogenboom, R.
Polymer Chemistry 2016, 7, 1705.
Duality of b-glucan microparticles: antigen carrier and immunostimulants
Baert S, De Geest BG, De Greve H, Cox E, Devriendt B.
International Journal of Nanomedicine 2016 11 2463
Hydrophilic thermoplastic polyurethanes for the manufacturing of highly dosed oral sustained release matrices via hot melt extrusion and injection molding
Verstraete G, Van Rentergem J, Van Bockstal PJ, Kasmi S, De Geest BG, De Beer T, Remon JP, Vervaet C
International Journal of Pharmaceutics 2016, 506, 214
Capsules with evolving brittleness to resist the preparation of self-healing concrete
Gruyaert E, Van Tittelboom K, Sucaet J, Anrijs J, Van Vlierberghe S, Dubruel P, De Geest BG, Remon JP, De Belie N
Materiales de Construccion 2016, 66, e092
2015
Transiently responsive protein-polymer conjugates via agrafting-from RAFT approach: for intracellular co-delivery of proteins and immune-modulators
Vanparijs, N., De Coen, R.; Laplace, D.; Louage, B.; Maji, S.; Lybaert, L.; Hoogenboom, R.; De Geest, B.G.
Chemical Communications, 2015, 51, 13972.
Acid-labile thermoresponsive copolymers that combine fast pH trigered hydrolysis and high stability at neutral condition
Zhang, Q.; Hou, Z.; Louage, B.; Zhou, D.; Vanparijs, N.; De Geest, B.G.; Hoogenboom R.
Angewandte Chemie International Edition, 2015, 54, 10879.
Tailoring cellular uptake of gold nanoparticles via the hydrophillic-to-hydrophobic ratio of their (co)polymer coating
Zhang, Z.; Van Steendam, K.; Maji, S.; Balcaen, L.; Anoshkina, Y.; Zhang, Q.; Vanluchene, G.; De Rycke, R.; Van Haecke, F.; Defroce, D.; Hoogenboom, R.; De Geest, B.G.
Advanced Functional Materials, 2015, 25, 3433-
Degradable ketal-based block copolymer nanoparticles for anti-cancer drug delivery: a systematic evaluation.
Louage, B.; Zhang, Q.; Van Parys, N.; Voorhaar, L.; Vande Casteele, S.; Shi, Y.; Hennink, W.E.; Van Bocxlaer, J.; Hoogenboom, R.; De Geest, B.G.
Biomacromolecules, 2015, 16, 336.
Polymer-protein conjugation via a 'grafting to' approach - a comparative study of the performance of protein-reactive RAFT chain transfer agents.
Vanparijs, N.; Maji, S.; Louage, B.; Voorhaar, L.; Laplace, D.; Zhang, Q.; Shi, Y.; Hennink, W.E.; Hoogenboom, R.; De Geest, B.G.
Polymer Chemistry, 2015, 6, 5602.
Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells
De Vlieghere, E.; Gremonprez, F.; Verset, L.; Mariën, L.; Christopher, J.J.; Decraene, B.; Berx, G.; Descamps, B.; Vanhove, C.; Remon, J.P.; Ceelen, W.; Demetter, P.; Bracke, M.; De Geest, B.G.; De Wever, O.
Biomaterials, 2015, 54, 148.
b-glucan microparticles targeted to epithelial APN as oral antigen delivery system
Baert, K.; De Geest, B.G.; De Rycke, R.; da Fonseca Antunes, A.B.; De Greve, H.; Cox, E.; Devriendt, B.
Journal of Controlled Release, 2015, 220, 149.
Solvent-free mechanochemical synthesis of a bicyclononyne tosylate: A fast route towards bioorthogonal clickable poly(2-oxazolines)s
Glassner, M.; Maji, S.; de la Rosa, V.R.; Vanparijs, N.; Ryskulova, K.; De Geest, B.G.; Hoogenboom, R.
Polymer Chemistry, 2015, 6, 8354.
Sequence-selective DNA recognition and enhanced cellular uptake by peptide-steroid conjugates
Ruiz Garcia, Y.; Ilyer, A.; Van Lysebetten, D.; Pabon, V.; Louage, B.; Honcharenko, M.; De Geest, B.G.; Smith, C.I¨.E.; Stromberg, R.; Madder, A.
Chemical Communications, 2015, 51, 17552.
Theremoresponsive polymer coated gold nanoparticles: from MADIX/RAFT copolymerization of N-vinylpyrrolidone and N-vinylcaprolactam to salt and temperature induced nanoparticle aggregation
Maji, S.; Zhang, Z.; Voorhaar, L.; Pieters, S.; Stubbe, B.; Van Vlierberghe, S.; Dubruel, P.; De Geest, B.G.; Hoogenboom, R.
RSC Advance 2015, 5, 42388.
One-pot preparation of inert well-defined polymers by RAFT polymerization and in-situ end group transformation
Zhang, Q.; Voorhaar, L; De Geest, B.G.; Hoogenboom, R.
Macromolecular Rapid Communications, 2015, 36, 1177.
Colorimetric Logic gates based on novel poly(\(\(\(2-alkyl-2-oxazoline) coated gold nanoparticles
De la Rosa, V.R.; Zhang, Z.; De Geest, B.G.; Hoogenboom R.
Advanced Functional Materials, 2015, 25, 2511.
Stapling monomeric GCN4 peptides allows fro DNA binding and enhanced cellular uptake
Iler, A.; Van Lysebetten, D.; Ruiz Garcia, Y.; Louage, B.; De Geest, B.G.; Madder, A.
Organic and Biomolecular Chemistry, 2015, 13, 3856.
Versatile Loading of Diverse Cargo into Functional Polymer Capsules
Richardson, J.; Maina, J.M.; Ejima, H.; Hu, M.; Guo; J.; Choy, M.Y.; ; Gunawan, Lybaert, L.; Hagemeyer, C.E.; De Geest, B.G.; Caruso, F.
Advanced Science 2015, 2
Linear polyethyleneimine as (multi)functional initiator for organocatalytic L-lactide polymerization
Coulembier, P.; Moins, S.; Maji, S.; Zhang, Z.; De Geest, B.G.; Dubois, P.; Hoogenboom, R.
Journal of Materials Chemistry 2015, 3, 612-619.
Rational design of injectable hexapeptide hydrogelators for controlled-release drug delivery
Bibain, M.; Mangelschots, J.; Gardiner, J.; Waddington, L.; Acevedo, M.M.D.; De Geest, B.G. Van Mele, B.; Madder, A.; Hoogenboom, R.; Ballet, S.
Journal of Materials Chemistry 2015, 3, 759.
2014 (10)
Bio-Hybrid Tumor Cell-Templated Capsules: A Generic Formulation Strategy for Tumor Associated Antigens in View of Anti-Cancer Immune-Therapy
Lybaert, L.; De Vlieghere, E.; De rycke, R.; Vanparijs, N.; De Wever, O.; De Koker, S.; De Geest, B.G.
Advanced Functional Materials, 2014, 24, 7139-7150.
Nanoporous hydrogen bonded polymeric microparticles: facile and economic production of cross presentation promoting vaccine carriers
Dierendonck, M.; Fierens, K.; De Rycke, R.; Lybaert, L.; Maji, S.; Zhang, Z.; Zhang, Q.; Hoogenboom, R.; Lambrecht, B.N.; Grooten, J.; Remon, J.P.; De Koker, S.; De Geest, B.G.
Advanced Functional Materials, 2014, 24, 4634-4644.
Nanoporous polyelectrolyte vaccine microcarriers - in vitro and in vivo evaluation
De Koker, S.; Fierens, K.; Dierendonck, M.; De Rijcke, R. Lambrecht, B.N.; Grooten, J.; De Geest, B.G.
Journal of Controlled Release, 2014, 195, 99-109.
Thermoresponsive hyaluronic acid nanogels as hydrophobic drug nanocarrier to macrophages
Fernandes Stefanello, T.; Szarpak-Jankowska, A.; Appaix, F.; Louage, B.; Hamard, L.; De Geest, B.G.; van der Sanden, B.; Vataru Nakamura, C.; Auzély-Veltya, R.
Acta Biomateriala, 2014, 10, 4750-4758
Hydrogen bonded Multilayer Films based on poly(2-oxazoline)s and tannic acid
Sundaramurthy, A.; Vergaelen, M.; Maji, S.; Auzely-Velthy, R.; Zhang, Z.; De Geest, B.G.; Hoogenboom, R.
Advanced Healthcare Materials, 2014, 3, 2040-2047.
Spray-Dried Polyelectrolyte Microparticles in Oral Antigen Delivery: Stability, Biocompatibility and Cellular Uptake
De Smet, R.; Verschuere, S.; Allais, L.; Leclercq, G.; Dierendonck, M ; De Geest, B.G. ; Van Driessche, I. ; Demoor, T.; Cuvelier, C.A.
Biomacromolecules, 2014, 15, 2301-2309.
Fast and accurate partial hydrolysis of poly(\(\(\(\(\(\(2-ethyl-2-oxazoline) into tailored linear polyethyleneimine copolymers
De la Rosa, V.R.; Bauwens, E.; Monney, B.D.; De Geest, B.G.; Hoogenboom, R.
Polymer Chemistry, 2014, 5, 4957-4967?
Just spray it - next generation of electrostatic assembly
Dierendonck, M.; De Koker, S.; De Rijcke, R.; De Geest, B.G.
Soft Matter, 2014, 10, 804-807.
Straightforward RAFT-procedure for the synthesis of heterotelechelic poly(\(\(\(\(\(\(acrylamides)
Wallyn, S.; Zhang, Z.; Driessen, F.; Pietrasik, J.; De Geest, B.G.; Hoogenboom, R.; Du Prez, F.E.
Macromolecular Rapid Communications, 2014, 35, 405-411.
Dual pH- and temperature-responsive RAFT-based block co-polymer micells and polymer-protein conjugates with transient solubility
Zhang, Q.; Vanparijs, N.; Louage, B.; De Geest, B.G.; Hoogenboom, R.
Polymer Chemistry, 2014, 5, 1140-1144.
2013
Salt plays a pivotal role in the temperature-responsive aggregation and layer-by-layer assembly of polymer-decorated gold nanoparticles
Zhang, Z.; Maji, S.; da Fonseca Antunes, A.B. De Rijcke, R.; Zhang, Q.; Hoogenboom, R.; De Geest, B.G.
Chemistry of Materials, 2013, 25, 4297-4303.
Hydrogen bonded polymeric multilayer films assembled below and above the cloud point temperature
Antunes, A.B.; Dierendonck, M; Vancoillie, G.J.; Remon, J.P.; Hoogenboom, R.; De Geest, B.G.
Chemical Communications, 2013, 49, 9663-9665.
Magnetically engineered microcapsules as intracellular anchors for remote control over cellular mobility
Pavlov, A.M.; De Geest, B.G.; Louage, B.; Lybaert, S.; De Koker, S.; Koudelka, Z.; Sapelkin, A.; Sukhorukov, G.B.
Advanced Materials, 2013, 25, 6945-6950.
Tuneable self-assembled nanogels composed of well-defined polymer-hyaluronic acid conjugates
Jing, J.; Alaimo, D.; De Vlieghere, E.; Jerome, C.; De Wever, O.; De Geest, B.G.; Auzely, R.
Journal of Materials Chemistry B, 2013, 1, 3883-3887.
b-glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination
De Smet, R.; Demoor, T.; Verschuere, S.; Dullaers, M.; Ostroff; G.R.; Leclercq, G.; Allais, L.; Pilette, C.;
Dierendonck, M.; De Geest, B.G; Cuvelier, C.A.
Journal of Controlled Release, 2013, 172, 671-678.
Improved anti-inflammatory effects in rabit eye model using biodegradable poly beta-amino ester nanoparticles of triamcinolone acetonide
Sabzevari, A.; Adibkia, K.; Hashemi, H.; De Geest, B.G.; Mohsenzadeh, N.; Atyabi, F.; Ghahremani, H.; Khoshanyand, M.R.; Dinarvand, R.
Investigative Ophtalmology & Visual Sciences, 2013, 54, 5520-5526.
Formulation of poorly water-soluble drugs via coacervation - a pilot study with febantel
De Jaeghere, W.; De Geest, B.G.; Remon, J.P.; Vervaet, V.; Antunes, A.B.
European Journal of Pharmaceutics and Biopharmaceutics, 2013, 85, 930-935.
Prilling of fatty acids as a continuous process for the development of controlled release multiparticulate dosage forms
Vervaeck, A.; Saerens, L.; De Geest, B.G.; De Beert, T.; Carleer, R.; Adriaensens, P.; Remon, J.P.; Vervaet, C.
European Journal of Pharmaceutics and Biopharmaceutics, 2013, 85, 587-595.
Structural Modifications of Polymethacrylates: Impact on Thermal Behavior and Release Characteristics of Glassy Solid Solutions.
Claeys, B.; De Coen, R.; De Geest, B.G. de la Rosa, V.R., Hoogenboom, R.; Carleer, R.; Adriaensens, P.; Remon, J.P.; Vervaet, C.
European Journal of Pharmaceutics and Biopharmaceutics, 2013, 85, 1206-1214.
Complexity from simplicity: unique polymer capsules, rods, monoliths and liquid marbles prepared via HIPE-in-microfluidics
Gokmen, M.T.; Dereli, B.; De Geest, B.G.; Du Prez, F.E.
Particle, 2013, 30, 438-444.
Mechanical strength and intracellular uptake of CaCO3-templatated LbL capsules composed of bio-degradable polyelectrolytes: the influence of the number of layers.
Delcea, M.; Palankar, R.; Pinchasik, B.; Schmidt, S.; De Geest, B.G.; Fery, A.; Möhwald, H.; Skirtach, A.G.
Journal of Materials Chemistry 2013, 1, 1175-1181.
One-step spray-dried polyelectrolyte microparticles enhance the antigen cross-presentation capacity of porcine dendritic cells.
Devriendt, B.; Baert, K.; Dierendonck, M.; Favoreel, H.; Remon, J.P.; De Geest, B.G.; Cox, E.
European Journal of Pharmaceutics and Biopharmaceutics, 2013, 84, 421-429.
Systematic processing of b-tricalcium phosphate for efficient protein loading and in vitro analysis of antigen uptake.
Kollath, V.O.; De Geest, B.G.; Mullens, S.; De Koker, S.; Luyten, J.; Persoons, R.; Traina, K.; Remon, J.P.; Cloots, R.
Advanced Engineering Materials, 2013, 15, 295-301.
Gelucire 44/14 based immediate release formulations for poorly water-soluble drugs.
Antunes, A.B.; De Geest, B.G.; Vervaet, C.; Remon, J.P.
Drug Development and Industrial Pharmacy, 2013, 39, 791-798.
2012
Surface engineered polyelectrolyte multilayer capsules – synthetic vaccines mimicking microbial structure and function.
De Geest, B.G.; Willart, M.A.; Lambrecht, B.N.; Vervaet, C.; Remon, J.P.; Grooten, J.; De Koker, S.
Angewante Chemie International Edition, 2012, 51, 3862-3866.
Polyelectrolyte multilayer capsules induce protective immunity against cancer and viral infection by targeting dendritic cells.
De Geest, B.G.; Willart, M.A.; Hammad, H.; Lambrecht, B.N.; De Filette, M.; Saelens, X.; Remon, J.P.; Grooten, J.; De Koker, S.
ACS Nano, 2012, 6, 2136-2149.
Polymeric multilayer capsules in drug delivery.
De Koker, S.; Hoogenboom, R.; De Geest, B.G.
Chemical Society Reviews, 2012, 41, 2867-2884.
Engineered 3D microporous gelatin scaffolds to study cell migration.
De Cock, L.J.; De Wever, O.; Hammad, H.; Lambrecht, B.N.; Vanderleyden, E.; Dubruel, P.; De Vos, F.; Vervaet, C.; Remon, J.P.; De Geest, B.G.
Chemical Communications, 2012, 48, 3512-3514.
Polyelectrolyte complexes and capsules for vaccine delivery.
Dierendonck, M.; De Koker, S.; Vervaet, C.; Remon, J.P.; De Geest, B.G.
Journal of Controlled Release, 2012, 161, 592-599.
Solvent-free drug crystal engineering for drug nano- & micro suspensions.
Antunes, A.B.; De Geest, B.G.; Vervaet, C.; Remon, J.P.
European Journal of Pharmaceutical Sciences, 2012, 48, 121-129.
Epithelial targeting for oral vaccination.
Devriendt, B.; De Geest, B.G.; Cox, E.
Journal of Controlled Release, 2012, 160, 431-439.
Redox-Responsive Degradable PEG Cryogels as Potential Cell Scaffolds in Tissue Engineering.
Dispinar, T.; Van Camp W.; De Cock, L.J.; De Geest, B.G.; Du Prez, F.E.
Macromolecular Bioscience, 2012, 12, 383-394.
Patchiness of embedded particles and film stiffness control through concentration of gold nanoparticles.
Kohler, D.; Volodkin, D.V.; Schmidt, S.; Madaboosi, N.; Delcea, M.; Schmidt, S.; De Geest, B.G.; Mohwald, H.; Skirtach,A.G.
Advanced Materials, 2012, 24, 1095-1100.
Engineered (hep/pARG)2 polyelectrolyte capsules for sustained release of bioactive TGF-1b.
De Cock, L.J.; De Wever, O.; Van Vlierberghe, S.; Vanderleyden, E.; Dubruel, P.; De Vos, F.; Vervaet, C.; Remon, J.P.; De Geest, B.G.
Soft Matter, 2012, 8, 1146-1154.
Partial hydrolysis of poly(2-ethyl-2-oxazoline) and potential implications for biomedical applications?
Van Kuringen, H.P.; Lenoir, J.; Adriaens, E.; Bender, J.; De Geest, B.G.; Hoogenboom, R.
Macromolecular Bioscience, 2012, 12, 1114-1123.
Targeting aminopeptidase N, a newly identified receptor for F4ac fimbriae, enhances the intestinal mucosal immune response.
Melkebeek, V.; Rasschaert, K; Bellot, P.; Tilleman, K.; Favoreel, H.; Deforcen, D.; De geest, B.G.; Goddeeris, B.M.; Cox, E.
Mucosal Immunology, 2012, 5, 635-645.
Poly(2-ethyl-E-oxazoline) as matrix excipient for drug formulation via hot melt extrusion and injection molding.
Claeys, B.; Vervaeck, A.; Vervaet, C.; Remon, J.P.; Hoogenboom, R.; De Geest, B.G.
Macromolecular Rapid Communications, 2012, 33, 1701-1707.
Highly versatile approach for preparing functional hybrid multisegmented nanotubes and nanowires.
Roy, C.J.; Chorine, N.; De Geest, B.G., De Smedt, S.C.; Jonas, A.M.; Demoustier-Champagne, S.
Chemistry of Materials, 2012, 24- 1562-1567.
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